* by AmLactin Ammonium Lactate… Ammonium Lactate Lotion, 12% is contraindicated in those patients with a history of hypersensitivity to any of the label ingredients. There are, however, no adequate and well-controlled studies in pregnant women. For Dermatologic Use Only … Lactic acid is an alpha-hydroxy acid. Ammonium lactate is usually applied twice a day. Caution is advised when used on the face because of the potential for irritation. Other reported clinical experience has not identified differences in responses between elderly and younger patients. AMMONIUM LACTATE- ammonium lactate lotion Less frequently occurring side effects include irritation, dryness, eczema, changes in skin color, or small … Lotions are thinner and lighter in consistency and can be used all over the body (for example, in case of eczema). The most frequent adverse experiences in patients with xerosis are transient stinging (1 in 30 patients), burning (1 in 30 patients), erythema (1 in 50 patients) and peeling (1 in 60 patients). It is a normal constituent of tissues and blood. ➺ It is available in the form of cream as well as lotion. In dermal Segment I and III studies with Ammonium Lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m2/day), approximately 0.4 times the human topical dose. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. Ammonium Lactate Lotion, 12% is available as follows: Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. ammonium lactate 12 % topical cream. It also contains cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Safety and effectiveness of ammonium lactate have been demonstrated in infants and children. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. Use twice daily or as directed by a physician. Ammonium Lactate Lotion 12%C-P , Fliptop - (400grams/14oz) - Pack of 2; Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube by Major Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube [2 PACK] AMMONIUM LACTATE 12% MOISTURIZING LOTION 226GM (8 OZ) EACH (PACK OF 2) *COMPARE TO THE SAME ACTIVE INGREDIENTS FOUND IN AMLACTIN & SAVE! Ammonium Lactate Cream, 12% also contains cetyl alcohol, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. Although lactic acid is a normal constituent of blood and tissues, it is not known to what extent this drug affects normal lactic acid levels in human milk. The oral administration of Ammonium Lactate to rats and mice showed this drug to be practically non-toxic (LD50>15 mL/kg). Evaluation of ammonium lactate in the treatment of seborrheic keratoses Maria V. Klaus, MD,a Richard F. Wehr, BS,b Roy S. Rogers III, MD,c Thomas J. Russell, MD: and Lincoln Krochmal, MOb Buffalo, New York, Rochester, Minnesota. imprint No data. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. Not for Ophthalmic, Oral or Intravaginal Use, We comply with the HONcode standard for trustworthy health information -, Lactic Acid and Ammonium Hydroxide Lotion. Shake the lotion form of this medication well just before using it. Because animal reproduction studies are not always predictive of human response, Ammonium Lactate Lotion, 12% should be used during pregnancy only if clearly needed. Because many drugs are excreted in human milk, caution should be exercised when Ammonium Lactate is administered to a nursing woman. This property may influence hydration of the stratum corneum. Sun exposure (natural or artificial sunlight) to areas of the skin treated with Ammonium Lactate Lotion, 12% should be minimized or avoided (see PRECAUTIONS). Perrigo New York Inc, For Dermatologic Use Only Because many drugs are excreted in human milk, caution should be exercised when ammonium lactate is administered to a nursing woman. Usual Dosage: Shake well. hydroxyzine, hydrocortisone topical, lidocaine topical, diphenhydramine, Benadryl, Eucerin, Aquaphor, AmLactin, dimethicone topical, CeraVe. Shake well. The oral administration of ammonium lactate to rats and mice showed this drug to be practically non-toxic (LD50>15 mL/kg). I use it on hands, feet, knees. Any ammonium lactate lotion will have this smell - I have used several brands with success. For lot number and expiration date, see bottle. * by AmLactin Ammonium Lactate; Third Edition Due to the more severe initial skin conditions associated with ichthyosis, there was a higher incidence of transient stinging, burning and erythema (each occurring in 1 in 10 patients). Apply to the affected areas and rub in thoroughly. An in vitro study of percutaneous absorption of Ammonium Lactate lotion, 12% using human cadaver skin indicates that approximately 5.8% of the material was absorbed after 68 hours. Distributed By Perrigo, Allegan, MI 49010. The alpha-hydroxy acids (and their salts) may act as … Clinical studies of ammonium lactate lotion, 12% did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. and Milwaukee, Wisconsin A double-blind, paired comparison study was used to evaluate treatment effects of 12% ammonium lactate lotion (Lac-Hydrin) against its … Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. Use twice daily or as directed by a physician. In dermal Segment I and III studies with ammonium lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m2/day), approximately 0.4 times the human topical dose. In general, dose selection for an elderly patient should be cautious. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Other adverse reactions which occur less frequently are irritation, eczema, petechiae, dryness, and hyperpigmentation. Ammonium lactate also prevents keratinization of epidermal skin layer, which keeps skin smoother and hydrated for a longer time. Apply to the affected areas and rub in thoroughly. The potential for post-inflammatory hypo- or hyperpigmentation has not been studied. Safety and effectiveness of Ammonium Lactate have been demonstrated in infants and children. However, a long-term photocarcinogenicity study in hairless albino mice suggested that topically applied 12% ammonium lactate formulations enhanced the rate of ultraviolet light-induced skin tumor formation. Apply ammonium lactate at around the same time (s) every day. Use twice daily or as directed by a physician. For lot number and expiration date, see bottle. Keep your skin looking smooth, vibrant and healthy with this Ammonium Lactate 12 Percent Cream. Many lotions and creams sting terribly and cause worse suffering, but Ammonium Lactate cream is so cooling and soothing and does not further irritate my sensitive skin. Apply to the affected areas and rub in thoroughly. Ammonium Lactate Lotion, 12% is contraindicated in those patients with a history of hypersensitivity to any of the label ingredients. Do not use in larger or smaller amounts or for longer than recommended. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This property may influence hydration of the stratum corneum. Clinical studies of Ammonium Lactate lotion, 12% did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. This topical medication is made from 12% lactic acid and ammonium hydroxide. The potential for post-inflammatory hypo- or hyperpigmentation has not been studied. *Ammonium Lactate Lotion, 12% specially formulates 12% lactic acid neutralized with ammonium hydroxide, as Ammonium Lactate to provide a lotion pH of 4.5 - 5.5. Set id: dc3a6462-0f2c-4306-b5ef-c7b47395e959, Not for Ophthalmic, Oral or Intravaginal Use, 225 g in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product, 400 g in 1 BOTTLE, PLASTIC; Type 0: Not a Combination Product. ➺ Ammonium lactate cream is available in 280 grams (two 140 gram… The mechanism(s) by which this is accomplished is not yet known. It is a moisturizer that is designed to treat the symptoms of dry, scaly skin conditions such as ichthyosis vulgaris and xerosis. The following image is a placeholder representing the product identifier that is either affixed or imprinted on the drug package label during the packaging operation. Not for Ophthalmic, Oral or Intravaginal Use. This medicine is a white, lotion ‹ Back to Gallery. Use twice daily or as directed by a physician. ammonium lactate 12 % lotion. Ammonium Lactate Lotion, 12% is available as follows: Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. ➺ Common brand names: Lac-Hydrin, AmLactin, Geri-Hydrolac, LAClotion, LAC Cream, Al-12 ➺ Generic name: ammonium lactate ➺ Drug class and mechanism: It is an anti-itch prescription medicine. Because animal reproduction studies are not always predictive of human response, Ammonium Lactate Lotion, 12% should be used during pregnancy only if clearly needed. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. Although lactic acid is a normal constituent of blood and tissues, it is not known to what extent this drug affects normal lactic acid levels in human milk. The use of Ammonium Lactate Lotion, 12% should be discontinued if any hypersensitivity is observed. No unusual toxic effects were reported. Ammonium Lactate Lotion, 12% is indicated for the treatment of dry, scaly skin (xerosis) and ichthyosis vulgaris, and for the temporary relief of itching associated with these conditions. This Ammonium Lactate cream infuses skin with moisture and smooths it out to give it a younger and healthier appearance. Patients using Ammonium Lactate Lotion, 12% should receive the following information and instructions: The topical treatment of CD-1 mice with 12%, 21% or 30% Ammonium Lactate formulations for two-years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. Ammonium lactate is an anti- itch topical medication formulated from 12% lactic acid and ammonium hydroxide. I think soaking is … Select one or more newsletters to continue. Other adverse reactions which occur less frequently are irritation, eczema, petechiae, dryness, and hyperpigmentation. Lactic acid is a racemic mixture of 2-hydroxypropanoic acid and has the following structural formula: Lactic acid is an alpha-hydroxy acid, it is a normal constituent of tissues and blood. No unusual toxic effects were reported. Get free shipping at $35 and view promotions and reviews for Amlactin Daily Moisturizing Body Lotion 12% Caution is advised when used on the face because of the potential for irritation. Use exactly as directed on the label, or as prescribed by your doctor. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. For external use only. Last updated on Sep 21, 2020. Patients using Ammonium Lactate Lotion, 12% should receive the following information and instructions: The topical treatment of CD-1 mice with 12%, 21% or 30% ammonium lactate formulations for two-years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Medically reviewed by Drugs.com. Due to the more severe initial skin conditions associated with ichthyosis, there was a higher incidence of transient stinging, burning and erythema (each occurring in 1 in 10 patients). Sadly, a small percentage of you may experience a negative reaction to the lotion. Stinging or burning may occur when applied to skin with fissures, erosions, or that is otherwise abraded (for example, after shaving the legs). However, a long-term photocarcinogenicity study in hairless albino mice suggested that topically applied 12% Ammonium Lactate formulations enhanced the rate of ultraviolet light-induced skin tumor formation. I have been given Lac Hydrin over the years but I hate it because it stings badly if any of your skin is irritated or cracked. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Apply to the affected areas and rub in thoroughly. Usual Dosage: Shake well. August 22, 2012 at 2:36 pm Ammonium lactate is commonly sold over the counter by the name of amlactin, LAC lotion, or LAC hydrin. Ammonium lactate hydrates the outermost skin layer and promotes skin moisturizing for a prolonged time. The most frequent side effect of using topical 12 percent ammonium lactate lotion is a stinging or burning sensation. Distributed By Perrigo, Allegan, MI 49010. The mutagenic potential of ammonium lactate formulations was evaluated in the Ames assay and in the mouse in vivo micronucleus assay, both of which were negative. Sun exposure (natural or artificial sunlight) to areas of the skin treated with Ammonium Lactate Lotion, 12% should be minimized or avoided (see PRECAUTIONS). The mechanism(s) by which this is accomplished is not yet known. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. It also contains cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. color white shape No data. Available for Android and iOS devices. Ammonium lactate comes as a cream and a lotion to apply to the skin. The mutagenic potential of Ammonium Lactate formulations was evaluated in the Ames assay and in the mouse in vivo micronucleus assay, both of which were negative. For external use only. This is a serious creme that provides incredible relief and promotes healing, but it is not a quick-absorb lotion so one will need gloves to help with absorption. Animal reproduction studies have been performed in rats and rabbits at doses up to 0.7 and 1.5 times the human dose, respectively (600 mg/kg/day, corresponding to 3600 mg/m2/day in the rat and 7200 mg/m2/day in the rabbit) and have revealed no evidence of impaired fertility or harm to the fetus due to Ammonium Lactate formulations. It is usually applied to the affected skin area twice daily. CONTAINS: *Ammonium lactate equivalent to 12% lactic acid, cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. I've been using it for years, including back when it was only available by prescription here. Amlactin Daily Moisturizing Body Lotion 12% at Walgreens. Other reported clinical experience has not identified differences in responses between elderly and younger patients. In general, dose selection for an elderly patient should be cautious. *Ammonium Lactate Lotion, 12% specially formulates 12% lactic acid neutralized with ammonium hydroxide, as ammonium lactate to provide a lotion pH of 4.5 - 5.5. Not for Ophthalmic, Oral or Intravaginal Use. Stinging or burning may occur when applied to skin with fissures, erosions, or that is otherwise abraded (for example, after shaving the legs). The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. The use of Ammonium Lactate Lotion, 12% should be discontinued if any hypersensitivity is observed. CONTAINS: *Ammonium Lactate equivalent to 12% lactic acid, cetyl alcohol, fragrance, glycerin, glyceryl stearate, laureth-4, light mineral oil, magnesium aluminum silicate, methylcellulose, methylparaben, PEG-100 stearate, polyoxyl 40 stearate, propylene glycol, propylparaben, and purified water. An in vitro study of percutaneous absorption of ammonium lactate lotion, 12% using human cadaver skin indicates that approximately 5.8% of the material was absorbed after 68 hours. Lac-Hydrin specially formulates 12% lactic acid, neutralized with ammonium hydroxide, as ammonium lactate to provide a lotion pH of 4.4-5.5. Lactic acid is a racemic mixture of 2-hydroxypropanoic acid and has the following structural formula: Lactic acid is an alpha-hydroxy acid, it is a normal constituent of tissues and blood. The following image is a placeholder representing the product identifier that is either affixed or imprinted on the drug package label during the packaging operation. There are, however, no adequate and well-controlled studies in pregnant women. Shake well. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. Animal reproduction studies have been performed in rats and rabbits at doses up to 0.7 and 1.5 times the human dose, respectively (600 mg/kg/day, corresponding to 3600 mg/m2/day in the rat and 7200 mg/m2/day in the rabbit) and have revealed no evidence of impaired fertility or harm to the fetus due to ammonium lactate formulations. The most frequent adverse experiences in patients with xerosis are transient stinging (1 in 30 patients), burning (1 in 30 patients), erythema (1 in 50 patients) and peeling (1 in 60 patients). Ammonium Lactate 12% Moisturizing Cream 140 Gm Flip-Top Tube [2 PACK] AMMONIUM LACTATE 12% MOISTURIZING LOTION 226GM (8 OZ) EACH (PACK OF 2) *COMPARE TO THE SAME ACTIVE INGREDIENTS FOUND IN AMLACTIN & SAVE! Rash and peeling skin may also occur. But the smell dissipates, and for many, it truly helps heal dry skin. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 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